E. K Herb Factory Supply Acetate Gossypol 98% Oligosaccharides 98% Gossypol 98% Cotton Seed Extract for Pharmaceutical Treatment

• Certification: ISO, Halal Kosher
• Assay Method: HPLC, UV
• Application Form: Paste, Tablet, Capsule
• Application: Food, Health Care Products, Medicine
• State: Powder
• Extract Source: 100% Natural
• Model NO.: EK-Cottonseed
• Product Name: Cotton Seeds Extract
• Latin: Urtica Cannabina L.
• Plant Part Used: Seed
• Active Ingredient: Acetate Gossypol, Raffinose, Oligosaccharides
• Color: Yellow Powder
• Grade: Food Grade, Medicine Grade
• Sample: Available
• Delivery Time: 3-5 Working Days
• MOQ: 1kg
• Shelf Life: 3 Years
• Storage: Keep in Cool & Dry Place, Stay Away From Strong Li
• Transport Package: 25kg/Drum
• Specification: 98%, 99%
• Trademark: E. K Herb/OEM
• Origin: China
• HS Code: 1302199099
• Production Capacity: 2t /Month

Product Description

E.K Herb Factory Supply Acetate Gossypol 98% Oligosaccharides 98% Gossypol 98% Cotton Seed Extract for Pharmaceutical Treatment

Cotton Seed is the seed of the cotton plant, whose mature seeds are brown ovoids weighing about a tenth of a gram. Gossypol is the active component extracted from cotton plant (genus Gossypium),which accounts for about 1.5% of the seeds in weight, and is mostly used as medicine in the form of Gossypol Acetate (cotton seed extract) , with function of permeating cells and acting as an inhibitor for several dehydrogenase enzymes.

Acetate Gossypol(cotton seed extract) has been tested as a male oral contraceptive in China, has also long been known to possess antimalarial properties. Clinical studies indicate that it has potent anti-tumor and anti-virus activity, and has been used for treating cancer of the adrenal cortex and cancer of the bladder.

Product Name	Cotton Seed Extract
Grade	Food/ Medical grade
Active Ingredient	Acetate Gossypol, Raffinose, Oligosaccharides
Appearance	White Powder Yellow Powder
Part Used	Seed
Specification	98%
Storage	Keep in cool & dry place, stay away from strong light and heat
Shelf Life	24 months

Function:

1. High concentrations of gossypol, function of enzyme or protein related cell growth, cell apoptosis, but not malignant hyperplasia induced cells

2.Gossypol acetic acid can make endometrial estrogen and progesterone in the dependence of acid phosphatase (ACP), nonspecific lipase (NSE) and alkaline phosphatase (AKP) activity decline, have indirect inhibition of endometrial cells.

 
3, inhibition of DNA synthesis of endometrial cells

Gossypol acetic acid can inhibit endometrial cells thymine and DNA synthesis, thereby directly inhibit the growth of endometrium atrophy.
High concentrations of gaa enzyme or functional protein can be related to cell growth, cell apoptosis, but not malignant hyperplasia induced cells.

4, Gossypol acetate on the regulation of ovarian hormones has a certain role.

Is mainly for hormone receptor inhibition at early stage, patients can reduce abnormal vaginal estrogen levels, but the serum estradiol, progesterone levels before and after ovulation had no effect.After a period of treatment, the serum hormone level decreased, but the natural recovery after the drug was stopped, does not affect fertility function.

5, The original secondary dysmenorrhea treatment effect
 

Gossypol acetic acid can inhibit the activity of lysosomal and the synthesis of DNA, which makes arachidonic acid into prostaglandins, this step is blocked, can inhibit the synthesis of prostaglandin and thrombosis.ACTS on the endometrium, can reduce endometrium metabolites prostaglandins and thromboxane in 6 - ketone - PGF1 alpha, TXB2 a significant therapeutic effect.
Compound gossypol acetate film contains vitamin B6, the use of vitamin B6 promote magnesium ions (mg++) through the cell membrane, increase the intracytoplasmic mg++ concentration effect, so as to play to the treatment of primary dysmenorrhea.

 

Application:

1. As a natural antioxidant, it is mainly used in cosmetic industry.

 

2. As a natural antioxidant, it is widely used in health product and food industry.

3. As raw materials of drugs for lowering cholesterol, anti-virus and anti-inflammatory, it is mainly used   in pharmaceutical field.

Certificate of Analysis

Analysis	Specification	Results
Assay(HPLC)	Raffinose ≥98%	98.31%
Appearance	White Crystalline Powder	Complies
Ash	≤5.0%	3.1%
Moisture	≤15.0%	13.8%
Pesticides	Negative	Complies
Heavy metals	≤10ppm	Complies
Pb	≤2.0ppm	Complies
As	≤2.0ppm	Complies
Hg	≤0.1ppm	Complies
Cd	≤0.1ppm	Complies
Odor	Characteristic	Complies
Particle size	100%through 30 mesh	Complies
Bulk density	0.40~0.50g/c	0.49
Optical rotation	105.5±2.5°	104.1°
PH	5.50~6.50	6.21
Residual ethanol	≤0.5%	0.08%
Melting point	78~82ºC	Complies
Microbioiogical:
Total of bacteria	≤1000cfu/g		Complies
Fungi	≤100cfu/g		Complies
Salmgosella	Negative		Complies
Coli	Negative		Complies
Storage     Store in cool & dry place. Do not freeze.                    Keep away from strong light and heat. Shelf life    2 years when properly stored

OTHER RECOMMEND HOT PRODUCTS

 

Hunan E.K Herb Co., Ltd.
Plant source	Main ingredient	Spec.(HPLC)
Eucommia leaf extract	Chlorogenic acid	5%-98%
Honeysuckle flower extract		5%-98%
Stevia extract		3%-20%
Rosemary extract	Carnosic acid	5%-95%
	Carnosic acid oil	5%-20%
	Ursolic acid	5%-98%
	Rosmarinic acid	5%-98%
Bitter almond extract	Amygdalin / VB17	98%
Mangosteen extract	Alpha-Mangostin	10%-90%
Milk Thistle	Silymarin / Silybin	5%-98%
Green tea extract	EGCG	90%-98%%
Tongkat Ali	Eurycomanone	1%-10% 100:1, 200:1
Monk Fruit Extract	Mogroside V	7%~98%
Valerian extract	Valeric acid	0.8%
Echinacea extract	Polyphenol	4.0%
	Chicoric acid	4.0%
Vine tea extract	Dihydromyricetin	98%
Polygonum cuspidatum extract	Resveratrol	98%
	Rheum Emodin	80%-98%
Magnolia bark extract	Magnolol	10%-98%
Pueraria extract	Puerarin	98%
Horny Goat Extract	Icariin	5%-98%
Rhodiola Rosea Extract	Salidroside	1%-98%
Schizandra P.E.	Schisandrin	1%-9%
Ginseng Extract	Gingosides	5%-80%
Centella Asiatica Extract	Asiaticoside	10%-95%
	Madecassoside	80%-95%
	Free Genins	80%-95%
	TECA	30%-95%
	Total Triterpenes	10%-80%
Jerusalem Artichoke	Inulin	90%~98%
NMN	β -nicotinamide mononucleotide	99%
PQQ	Pyrroloquinoline Quinone Disodium Salt	99%
Coenzyme Q10	Coenzyme Q10	99%
Alpha-Lipoic acid	Alpha-Lipoic acid	98%

Hunan E.K Herb Co.,Ltd. founded in 2010, is a modern high-tech enterprise committed to plant functionality, the extraction and purification of active ingredients.Based on the construction of a high starting point, the company has the domestic leading plant extract production line, is a refined production workshop with nearly 3000 square meters and nearly 20 mu of standardized crude lifting production workshop of large-scale production enterprises, its core technology in the leading position in the domestic peers.E.K Herb with advanced production equipment and high-tech research and development level, characterized by high quality product quality, on the basis of integrity service consciousness and high level of service attitude, constantly launch new products, improve the enterprise platform, improve the corporate image, serve the society, just to create greater social value and economic benefits.

E.K Herb mainly features high purity products,such as Chlorogenic acid 98%, Ursolic acid 98%,Rosmarinic acid 98%,Carnosic acid 95% ,Amygdalin 98%, Dihydromyricetin 98%, Resveratrol 98%, EGCG 95%,, and personalized product demand, we use technical advantages, and strong research and development ability, to provide product customization and research and development outsourcing services, to meet the needs of different customers.The scope of products covers chemical industry, medicine, food, cosmetics and other fields, in the past ten years, E.K Herb has always uphold the spirit of ingenuity, to ensure the quality, with first-class quality second-rate prices, specifications, fast and thoughtful service by the majority of users.And applied for the five invention patents of "high purity green raw acid preparation process" ,"high purity lycopene preparation process", "High purity Rosemary acid preparation process", "High purity Ursolic acid preparation process", "High purity Amygdalin preparation process",and successfully passed the QS, 1S09001 and other certification.

                    ABOUT US
 

E.K Herb insists in the principle of Top Quality, Excellent Service, Outstanding R&D innovation, Best After-sale Services.

E.K Herb adheres to the spirit of excellence and continuous innovation, strives for the develop and booms of the plant extract industry!

To be your faithful and reliable partner!

E.K Office, R&D

 

 E.K Factory

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Packing & Shipping

 

 

Packing 
* Delivery Time: Around 3-5 workdays after your payment.
* Package: In fiber-drums with two plastic bags inside.
* Net Weight: 25kgs/drum,Gross Weight: 28kgs/Drum
* Drum Size & Volume: I.D.42cm × H52cm, 0.08 m³/ Drum
* Storage: Stored in dry and cool place, keep away from strong light and heat.
* Shelf Life: Two years when properly stored.
shipping
* DHL Express, FEDEX and EMS for quantity less than 50KG, usually called as DDU service.
* Sea shipping for quantity over 300KG; and air shipping is available for 50KG above.
* For high value products, please select air shipping and DHL express for safe.
* Please confirm if you can make the clearance when goods reach your customs before placing an order. For buyers from Mexico, Turkey, Italy, Romania, Russia, and other remote area.
 

 

FAQ

Q1: What's the difference between herb extract and powder?
A: The extract is a concentrated powder form of raw material. The herb extract's procedure flow is wash, extraction, concentration, purification, drying, grinding, sieving, package. The herb powder is just a powder form of the herb. The procedure flow is wash, drying, grinding, sieving, package.

Q2: What's the extract solvent used in the procedure?
A: The extract solvent is always depending on the active ingredient in the raw material, regulation and customers' requirement. The solvents mostly used for extraction are water and ethanol. Even the solvent other than water used in the procedure, the solvent residue in the extract product also can conform with ICH Q3CR5.

Q3: Is there any other ingredient used in the product?
A: It depends. For product which is hard to be dried, we need to add some maltodextrin into the extraction solution before drying. The maltodextrin we used is food-class carrier, from non-GMO corn. We can share customer with the ingredient composition table.

Q4: How to make sure the quality of the product?
A: Firstly, every batch finish product must be tested and qualified before delivery. We can send a specification sheet or CoA for confirmation. The HPLC chromatography graph also can be provided. Secondly, we can provide pre-ship sample to customer for quality confirmation. 

Q5: Can you develop a new product for us?
A: Yes, we can. We have independent R&D dept, who is able to update the procedure parameters of our main products and develop the procedure of new product. For more information, please contact us directly.

Q6: Can you offer this in capsules or tablets as well?
A: Yes, we have related equipment for preparation of finish product, like tablet, capsule and granule. Kindly contact with us for details.

Q7: What is the MOQ?
A: For most of the products we already have in stock, the MOQ is 1kg. If the product is a new specification and need to be produced from raw material, the MOQ depends.

Q8: Is there any discount?
A: Yes, for larger quantity or better payment period, we can support with better price.

Q9: How about delivery time?
A: For most products, the product can be sent out from factory in 5days. If we don't have inventory, the product need to produced from raw material, the ordinary period is 20-25days.

Q10: How do you treat with quality complaint?
A: We will always be responsible for the quality of our products. If there's a complaint, we will first assist customers to solve the most direct needs.
Secondly, we have SOP for quality complaint. QA will investigate the problem, after that we'll give customer a timely feedback about the cause of the quality issue and related precautions for this problem.