E.K Herb Factory Free Sample Piperine Black Pepper Extract with Effect of Promoting Penetration High Quality CAS 94-62-2 Piperine 98%/ Black Pepper Extract
Piperine is the alkaloid responsible for the pungency of black pepper and long pepper, along with chavicine (an isomer of piperine).Piperine is often added to prepared food to enhance aroma and can Promote drug absorption, and improve the effectiveness of the drug function. In clinical practice, it can induce calm (sedative effect) or to induce sleep (hypnotic effect), and used to make anticonvulsant, antidepressant, and muscle relaxation drug.
Piperine has also been found to inhibit human CYP3A4 and P-glycoprotein, enzymes important for the metabolism and transport of xenobiotics and animal studies, piperine also inhibited other enzymes important in drug metabolism.By inhibiting drug metabolism, piperine may increase the bioavailability of various compounds.
| Product name |
Black Pepper Extract |
| Active ingredient |
Piperine |
| Botanical source |
Piper nigrum L. |
| CAS NO. |
94-62-2 |
| Specification |
50%,95%-98% Piperine ,10:1 |
| Molecular formula |
C17H19NO3 |
| Molecular Weight |
285.34 |
| Characters |
Light Yellow powder |
Piperine can be used in conjunction with various other supplements to enhance their potency by increasing bioavailability. The most apt example of this synergy is taking piperine while supplementing with curcumin. Curcumin has a very poor bioavailability because it is rapidly metabolized in the liver and intestinal wall. Piperine can slow both gastric emptying and intestinal transit, meaning that curcumin has a longer period of time to be exposed to potential uptake.
One study found that piperine supplementation increased the bioavailability of curcumin by 2000%. Another study found that piperine supplementation also improved the bioavailability of resveratrol.Piperine inhibits the drug transporter P-glycoprotein as well as the major drug-metabolizing enzyme CYP3A4. This is important because many drugs are substrates of these enzymes, meaning that these enzymes break down many drugs; when these enzymes are inhibited they are unable to do so and so the drugs last longer and are able to be absorbed more by the body.
As a traditional herbal medicine, black pepper is used to treat many diseases and is one of the important herbs. As early as the end of the 19th century, piperine, the main component of pepper, had been purified and synthesized, but there were few studies on its pharmacological effects. With the development of modern pharmacological techniques, the pharmacological action of piperine has been further understood.Studies have proved that piperine has sedative, hypnotic, anticonvulsive, skeletal muscle relaxation and anti-depression pharmacological effects
Functions :
1.It has the function of treatment for arthritis, rheumatism and skin disease or wound healing;
2. It has the function of losing weight, its ability to increase in the metabolic rate of the body;
3. It has the function of clearing heat and diuretic, expectorant, sedative and analgestic;
4. It has the function of treating acute conjunctivitis, bronchitis, gastritis, enteritis and urinary stones;
5. It has the function of enhancing immunity and supporting the intestinal absorption of nutrients.
Applications:
1.Piperine can be applied as pharmaceutical raw materials for arthritis, rheumatism, anti-inflammation, detumescence and so on, it is mainly used in pharmaceutical field.
2.Piperine can be applied as effective ingredients for improving blood circulation and soothing the nerves, it is mainly used in health product industry.
3.Piperine can be applied as active ingredients of skin care products, it is mainly used in cosmetic industry.
Certificate of Analysis
| Product Name |
Black Pepper Powder |
| Latin Name |
Piper nigrum |
| Item |
Specification |
Results |
Methods |
| Marker Compound |
Piperine 95% |
95.26% |
HPLC |
| Appearance & Color |
Light yellow powder |
Conform |
GB5492-85 |
| Odor & Taste |
Characteristic |
Conform |
GB5492-85 |
| Extract Solvent |
Water&Ethanol |
Conform |
|
| Bulk Density |
0.4-0.6g/ml |
0.45-0.55g/ml |
|
| Mesh Size |
80 |
100% |
GB5507-85 |
| Loss on Drying |
≤5.0% |
3.14% |
GB5009.3 |
| Ash Content |
≤5.0% |
1.26% |
GB5009.4 |
| Solvent Residue |
Negative |
Conform |
GC |
| Heavy Metals |
| Total Heavy Metals |
≤10ppm |
<3.0ppm |
AAS |
| Arsenic (As) |
≤1.0ppm |
<0.2ppm |
AAS(GB/T5009.11) |
| Lead (Pb) |
≤1.0ppm |
<0.4ppm |
AAS(GB5009.12) |
| Cadmium |
<1.0ppm |
Not Detected |
AAS(GB/T5009.15) |
| Mercury |
≤0.1ppm |
Not Detected |
AAS(GB/T5009.17) |
| Microbiology |
| Total Plate Count |
≤5000cfu/g |
Conform |
GB4789.2 |
| Total Yeast & Mold |
≤300cfu/g |
Conform |
GB4789.15 |
| Total Coliform |
≤40MPN/100g |
Not Detected |
GB/T4789.3-2003 |
| Salmonella |
Negative in 25g |
Not Detected |
GB4789.4 |
| Staphylococcus |
Negative in 10g |
Not Detected |
GB4789.1 |
| Packing and Storage |
25kg/drum Inside: Double-deck plastic bag, outside: Neutral cardboard barrel & Leave in the
shady and cool dry place |
| Shelf Life |
3 Years When Stored properly |
| Expiration Date |
3 Years |
| Note |
Non-Irradiation&ETO,Non-GMO,BSE/TSE Free |
Hunan E.K Herb Co.,Ltd. founded in 2010, is a modern high-tech enterprise committed to plant functionality, the extraction and purification of active ingredients.Based on the construction of a high starting point, the company has the domestic leading plant extract production line, is a refined production workshop with nearly 3000 square meters and nearly 20 mu of standardized crude lifting production workshop of large-scale production enterprises, its core technology in the leading position in the domestic peers.E.K Herb with advanced production equipment & high-tech research and development level, characterized by high quality product quality, on the basis of integrity service consciousness and high level of service attitude, constantly launch new products, improve the enterprise platform, improve the corporate image, serve the society, just to create greater social value and economic benefits.
E.K Herb mainly features high purity products,such as Chlorogenic acid 98%, Ursolic acid 98%,Rosmarinic acid 98%,Carnosic acid 95% ,Amygdalin 98%, Dihydromyricetin 98%, Resveratrol 98%, EGCG 95%,, and personalized product demand, we use technical advantages, and strong research and development ability, to provide product customization and research and development outsourcing services, to meet the needs of different customers.The scope of products covers chemical industry, medicine, food, cosmetics and other fields, in the past ten years, E.K Herb has always uphold the spirit of ingenuity, to ensure the quality, with first-class quality second-rate prices, specifications, fast and thoughtful service by the majority of users.And applied for the five invention patents of "high purity green raw acid preparation process" ,"high purity lycopene preparation process", "High purity Rosemary acid preparation process", "High purity Ursolic acid preparation process", "High purity Amygdalin preparation process",and successfully passed the QS, 1S09001 and other certification.
E.K Herb adheres to the spirit of excellence and continuous innovation, and strives for the development and take-off of the plant extract industry!We will always be with the strictest product safety standards, the best product quality, the most intimate service level, wholeheartedly to serve you!
Office & Factory
Exhibition
E.K Herb Team Building
Packing
* Delivery Time: Around 3-5 workdays after your payment.
* Package: In fiber-drums with two plastic bags inside.
* Net Weight: 25kgs/drum,Gross Weight: 28kgs/Drum
* Drum Size & Volume: I.D.42cm × H52cm, 0.08 m³/ Drum
Shipping
* DHL Express, FEDEX and EMS for quantity less than 50KG, usually called as DDU service.
* Sea shipping for quantity over 500KG; and air shipping is available for 50KG above.
* For high value products, please select air shipping and DHL express for safe.
FAQ:
| Q1: Can i get some samples? |
| A: Yes, we can supply the free sample, but the shipping cost be paid by our customers. |
| |
| Q2: How to start orders or make payments? |
| A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union |
| or Paypal or Escrow(Alibaba). |
| |
| Q3: How to confirm the Product Quality before placing orders? |
| A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the |
| samples. You can send us your product specifications and requests,we will manufacture the products according to your requests. |
| |
| Q4:What's your MOQ? |
| A:Our MOQ is 1kg or 10g(Different products have different MOQs). But usually we accept less quantity such as 10g on the condition that sample charge is 100% paid. |
| |
| Q5: How about delivery leadtime? |
| A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included) |
| |
| Q6:Is there a discount? |
| A:Different quantity has different discount. |
| |
| Q7: How do you treat quality complaint? |
| A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, |
| we will send you free goods for replacement or refund your loss. |
| |
| Q8: How to contact us ? |
| A:You can chat with us by Trademanager Online. You can choose your interested products and send inquiry to us. |
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